Creatine Creatine is a naturally taking place substance within our muscle cells, and it is one of the fundamental sources of mobile energy. Whenever you blink your eyes, scratch your elbow, chunk your food, or perform most different movements, it’s creatine—or rather, the creatine phosphate power system—that’s powering you via it. As a supplement, creatine has been popular considering the 1990s, and has been the situation of hundreds of .